当前细菌抗药性探析

Analysis of Bacterial Drug Resistance

目的对当前细菌抗药性进行分析。方法对我院于2012年4月~2013年5月采集、分离1800株病原菌进行药物敏感性试验结果进行分析。结果在1800株病原菌中,革兰氏阴性菌1080株(60.00%),革兰氏阳性菌503株(27.94%),真菌217株(12.06%)。铜绿假单胞菌对各种常用抗生素均具有较强耐性,且三代与第四代头孢类抗生素病原菌抗药性不断增强。结论在抗生素临床应用中,应以病菌药敏试验结果为依据,选择病菌敏感性抗生素,才能提高治疗效果,降低致病菌抗药性。

Objective To analyze the drug resistance of bacteria.Methods In our hospital from 2012 April to 2013 May acquisition,isolated 1800 strains of pathogenic bacteria drug sensitivity test results.Results Among 1800 strains of pathogens,gram negative bacil i 1080 isolates(60%),gram positive bacil i 503 isolates(27.94%),217 strains of fungi(12.06%).Pseudomonas aeruginosa has strong resistance to commonly used antibiotics,and the three and fourth generation cephalosporin antibiotic resistance of pathogens growing.Conclusion In the clinical application of antibiotics to bacteria,should be based on the drug sensitivity test,selection of antibiotic susceptibility of bacteria,can improve the treatment ef ect,reduce pathogenic bacteria resistance.