黛力新与甘淮大枣汤综合治疗躯体性焦虑疗效和副反应观察

A Comparative Study of Flupentixol & Melitracen Tablets Versus ganhuaidazao in Treatment of Somatization Disorder

目的探讨黛力新与甘淮大枣汤治疗躯体性焦虑的疗效和副反应。方法66例患者按就诊先后随机分为治疗组和对照组,分别进行黛力新与甘淮大枣汤治疗4w,于治疗前及治疗后分别进行汉密顿焦虑量表(HAMA)、四级临床疗效及安全性的评估。结果两组总有效率分别为82.25%、54.83%,两组间疗效差异有显著性(值<0.01),甘淮大枣汤组未见明显不良反应,黛力新组不良反应发生率为2.01%,主要为轻度恶心。结论黛力新治疗躯体性焦虑疗效较好,副作用少。

Objective To explore the therapeutic ef icacy and side-ef ects of Flupentixol and Melitracen Tablets for somatization disorder compared with ganhuaidazao.Methods 66 patients were divided at random into therapy group treated with Flupentixol&Melitracen Tablets and control group with ganhuaidazao respectively for 4 weeks.The status of the patients was assessed before and after treatment with HAMD,TESS,Fourgrade clinical assessing criteria and the results of laboratory tests to compare the therapeutic ef icacy and side effects of Flupentixol&Melitracen Tablets with ganhuaidazao.Results The total ef ective rate was 82.25%in therapy group and 54.83%in control group respectively.Significant dif erence was found between two groups.The incidence of side ef ects in therapy group was 2.01%,but no evident side ef ects was found in control group.Conclusion The therapeutic ef icacy of Flupentixol&Melitracen Tablets for somatization disorder is significant with less side ef ects.