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急性肺损伤的治疗进展 被引量:2

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摘要 急性肺损伤(acute lung injury,ALI )是临床常见的危重症,它是指在严重感染、休克、创伤及烧伤等非心源性疾病过程中,肺毛细血管内皮细胞和肺泡上皮细胞损伤造成弥漫性肺间质及肺泡水肿,而导致的急性低氧性呼吸功能不全或呼吸功能衰竭。其病理生理特征为肺顺应性降低、肺容积减少、和严重的通气/血流比值失调,以进行性低氧血症和呼吸窘迫为主要的临床表现,肺部X线表现为非均一性的渗出性病变[1]。继续恶化,发展成急性呼吸窘迫综合症(acute respiratory distress syndrome,ARDS)。由于ALI病死率高达40%~50%,疗效差,是临床比较棘手的问题,现就ALI的治疗进展综述如下。
作者 吴振宇
出处 《医学信息(医学与计算机应用)》 2014年第10期497-498,共2页 Medical Information
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