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贝伐单抗治疗穿透性角膜移植术后新生血管对全身的影响

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摘要 目的:观察贝伐单抗用于治疗穿透性角膜移植术后新生血管,全身血液中VEGF和免疫功能含量变化。方法对12例(12眼)穿透性角膜移植术后新生血管增生患眼,球结膜下分别注射贝伐单抗和设立空白对照组,1次/月,共2次。于注药前1d,后1d,1月分别检测血液中VEGF和免疫功能的含量。结果注射贝伐单抗组角膜新生血管面积明显减小。全身血液中VEGF和免疫功能的含量均无变化。结论穿透性角膜移植术后球结膜下注射贝伐单抗对全身VEGF含量和免疫功能无影响。
出处 《医学信息(医学与计算机应用)》 2014年第10期392-392,393,共2页 Medical Information
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