卡前列素氨丁三醇预防剖宫产产后出血的临床疗效观察

Clinical Investigation Observation of Preventive Effect of Carboprost Tromethamine on Postpartum Hemorrhage in Patients of Cesarean Section

目的:探讨剖宫产术中宫体注射卡前列素氨丁三醇预防产后出血的临床疗效。方法选取我院产科2011年10月~2013年10月住院行剖宫产分娩的产妇100例,将产妇随机分成两组,为预防产后出血,观察组术中于宫体注射缩宫素及卡前列素氨丁三醇,对照组术中仅应用缩宫素,评价二者的临床效果。结果观察组患者产后2h平均出血量为(201.3±54.1)ml,24h平均出血量为(299.7±74.6)ml,与对照组相比明显减少(P<0.01);观察组患者中有9例发生产后出血,产后出血的发生率为18%,与对照组相比明显降低(P<0.01)。观察组中有3例输血,输血率为6%,与对照组相比降低(P<0.05)。讨论卡前列素氨丁三醇在剖宫产术中能有效降低产后出血率,减少术后出血量,安全,有效,在产后的提前预防中具有良好的临床价值。

Objective To investigate the ef icacy of carboprost tromethamine on postpartum hemorrhage in patients of cesarean section.Methods 100cases of pregnant women with indication of cesarean section in our hospital from Oct 2011 to Oct 2013 were divided into the observation group and control group,to prevate postpartum hemorrhage,patients in observation group were given Oxytocin and carboprost tromethamine,the patients in control group were given Oxytocin.The information of average 2 h and 24 h bleeding quantity of postpartum,the heincidence rate of postpartum hemorrhage and blood transfusion were col ected and compared after the therapy.Results The bleeding quantity of 2 h postpartum of control group was(335.9±57.3)ml,while that of the observation group was(201.3±54.1)ml,the dif erences were significant(P<0.01);The average decreased quantity of 24 h postpartum of control group was(421.4±73.4)ml,obviously higer than observation group.The incidence rate of postpartum hemorrhage and blood transfusion of control group was obviously higher than observation group,the dif erences were significant.Conclusion Carboprost tromethamine can obviously reduce blood loss after cesarean section.It can be recognized as a safe,ef icient and convenient method in preventing postpartum hemorrhage after cesarean section.