摘要
目的:该篇META分析比较右室非心尖部起搏(RVNAP)和心尖部起搏(RVAP)对心功能的影响。方法检索 MEDLINE、EMBASE和 Cochrane Control ed Trials Register数据库,收集随访时间≥2个月的随机对照试验。结果20个试验包括1114例患者入选。与 RVAP相比,RVNAP不仅在起搏阈值及 R波感知方面表现优异,左室射血分数在随访末也明显升高。结论 RVNAP在电极参数方面表现出令人满意的长期结果,并在6个月随访后,提高左室射血分数方面作用有利。
Objective A meta-analysis of randomized control ed trials(RCTs)was conducted to compare the ef ects of right ventricular nonapical(RVNA)and right ventricular apical(RVA)pacing on cardiac function.Methods A systematic literature search was performed using MEDLINE,EMBASE,and the Cochrane Library to identify RCTs comparing RVNA pacing with RVA pacing with fol ow-up≥2 months.Results Twenty RCTs involving 1,114 patients were included.Compared with RVA pacing,RVNA pacing exhibited not only excellent pacing threshold and R-wave amplitude but also higher impedance.RVNA pacing showed a significant increase in left ventricular ejection fraction(LVEF)at the end of fol ow-up.Conclusion This meta-analysis found that RVNA pacing exhibited satisfactory long-term lead performance compared with RVA pacing and demonstrated beneficial ef ects in improving LVEF after the 6-month fol ow-up.
作者
王蔚宗
尹香翠
张玉娇
WANG Wei-zong;YIN Xiang-cui;ZHANG Yu-jiao(Shandong University,Jinan 250014,Shandong,China;Shandong Qianfoshan Hospital,Jinan 250014,Shandong,China)
基金
山东省医药卫生科技发展计划项目,项目号2011WSB04013。
关键词
META分析
右室非心尖部起搏
心功能
文献检索
META Analysis
Right Ventricular Nonapical Pacing
Cardiac Function
Literature Retrieval
