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先天性心脏病患者Nkx2.5基因突变研究 被引量:2

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摘要 目的对先天性心脏病患者Nkx2.5基因进行突变观察及关联研究。方法分别对50例先天性心脏病病例及50例对照组Nkx2.5基因全部外显子扩增并测序。结果在Nkx2.5识别出了1个不改变氨基酸的单核甘酸多态,即c.63A>G多态,但此多态无统计学意义(>0.05)。结论 Nkx2.5基因的c.63A>G多态可能与CHD有关。
出处 《医学信息(医学与计算机应用)》 2014年第18期193-193,194,共2页 Medical Information
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