摘要
目的:探讨培美曲塞联合卡铂治疗老年晚期非小细胞肺癌的安全性、有效性及护理对策。方法纳入经病理学确诊的老年晚期非小细胞肺癌患者75例,给予培美曲塞联合卡铂治疗,治疗后观察其临床疗效和毒副反应,并针对围治疗期采取的相应护理措施进行总结分析。结果全组75患者治疗总有效率44.00%,疾病控制率73.33%。毒副反应主要为骨髓抑制、胃肠道反应,经过对症处理及精心护理均可耐受,未影响化疗的顺利进行。结论培美曲塞联合卡铂治疗老年晚期非小细胞肺癌具有一定疗效,经过对症处理和精心护理干预毒副反应患者也可耐受。
Objective To investigate the clinical ef icacy and nursing intervention of pemetrexed plus carboplatin in the treatment of elderly patients with advanced non-smal celllung cancer.Methods Seventy-five elderly patients with advanced non-smal celllung cancer received pemetrexed plus carboplatin,the clinical ef icacy and toxicities after treatment were observed,the nursing measures were summarized.Results The 75 patients,the total ef ective rate was 44.00%,the disease control rate was 73.33%.The main toxicities were myelosuppression and gastrointestinal reactions,were tolerated after symptomatic treatment and intensive nursing.Conclusion Pemetrexed plus carboplatin is ef ective for elderly patients with advanced non-smal celllung cancer,the toxicities can be tolerated after symptomatic treatment and intensive nursing.
作者
许克璞
徐丽娟
刘英杰
XU Ke-pu;XU Li-juan;LIU Ying-jie(The 152th Hospital of PLA,Pingdingshan 467000,Henan,China)
关键词
非小细胞肺癌
培美曲塞
卡铂
护理
Non-smal celllung cancer
Pemetrexed
Carboplatin
Nursing