摘要
目的:混合门冬胰岛素302次/d注射(诺和锐30)与预混人胰岛素(诺和灵30R 30R)在2型糖尿病患者治疗的安全性的疗效。方法68例口服降糖药控制不佳的2型糖尿病患者随机分为两组,诺和锐30治疗组与诺和灵30R治疗组,分别,每日早餐前晚餐前诺和锐30与诺和灵30R注射。观察12 w。比较两组患者的糖化血红蛋白(HbAlc),血糖,低血糖的频率等。结果早期诺和锐30治疗组。餐后血糖显著低于诺和灵30R治疗组(P<0.01);门冬胰岛素30治疗组低血糖比诺和灵30R治疗组少,但差异无统计学意义(P>0.05),门冬胰岛素治疗组无严重低血糖。结论2型糖尿病患者。2次/d注射门冬胰岛素30比诺和灵30R显著降低餐后血糖,降低低血糖风险,易为患者接受。
Objective Mixed insulin aspart 302 infusions of/d(Nuo Herui 30)mixed human insulin(Novolin 30R and pre 30R)on the ef icacy and safety of treatment of type 2 diabetic patients.Methods 68 cases of oral antidiabetic drug control in type 2 diabetic patients were randomly divided into two groups of poor,insulin aspart 30 in treatment group and Nuo Heling 30R treatment group,respectively,every morning before breakfast before supper insulin aspart 30 and Nuo Heling 30R injection.Observation of 12 W.Comparing the two groups of patients with glycosylated hemoglobin(HbAlc),blood glucose,and frequency of hypoglycemia etc.Results The early insulin aspart 30 in the treatment group.Postprandial blood glucose was significantly lower than that of Novolin 30R treated group(P<0.01);insulin aspart 30 in treatment group and 30R treatment group hypoglycemia noir spirit less,but the dif erence was not statistical y significant(P>0.05),insulin aspart treatment group without severe hypoglycemia.Conclusion Patients with type 2 diabetes mel itus.The 2/d injection of insulin aspart 30 Noir and spirit of 30R significantly decreased the postprandial blood glucose,reduce the risk of hypoglycemia,the patient is easy to accept.
作者
肖义琼
XIAO Yi-qiong(The Second People's Nankang City,Nankang 341411,Jiangxi,China)
