摘要
目的采用体外血清学检测方法检测变应性疾病患者的变应原,并按年龄段分组进行比较分析。方法对2012年7月~11月我院门诊就诊的变态反应患者共535例,采用德国Mediwess公司生产的Al ergy Screen系统进行变应原的slgE血清学检测。结果①儿童组变应原检出阳性率为73.14%,高于其他各年龄段;于不同年龄段的变应原分布有差异,吸入性变应原中,slgE阳性率最高者为户尘螨,占78.5%;儿童组户尘螨lgE阳性率又高于其他各年龄段,为89.74%;③对吸入性变应原,户尘螨组及猫狗皮屑组不同年龄段的slgE的检测值有明显差异[1],对户尘螨slgE的检测值,儿童组与其他各年龄段的差异最为明显(=2.018,3.174,3.476;=0.045,0.002,0.001)。结论不同变应原检测阳性率及其与总体阳性率随年龄变化的分布趋势不完全一致。同时slgE的检测值,儿童组与其余各组的差异也最大。建议对儿童的变应性疾病应早期进行干预。
Objective Al ergen detection in ptients with al ergic disease using serologicl detection method,analzing and comparing by age group.Methods For patients in our hospital during November 2012 to July a total 535 al ergic reaction,slgE serological detection of al ergen by Al ergyScreen system manufactured by Mediwess company in Germnay.Results①Children al ergen positive rate was 73.14%,higher than the other age.②Distributions of al ergens of dif erent ages have dif erent,inhaled al ergens,the positive rate of slgE was highest in Dermatophagoides pteronyssinus 78.5%,children dermatophagoides pteronyssinus lgE positive rate was higher than the other age groups,89.74%.③For inhalation al ergen detection of dif erent ages,the values of slgE are significantly dif erent for house dust mite and cat dog dander group,detection of house dust mite slgE values,different groups of children and other age is the most obvious(=2.018,3.174,3.476;=0.045,0.002,0.001).For food al ergens in children group for milk,and the other three groups were significnt dif erences(=2.163,2.338,2.370,p=0.026,0.021,0.02).Conclusion Distribution of positive rate in different al ergens and the positive rate of the overal change with age is not consistent.At the same time,slgE detection value differences of children group and other groups also has the largest.Recommended intervention on early al ergic diseases of children.
作者
魏峻
WEI Jun(Department of Otolaryngology Head and Neck Surgery,Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China)
