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胃癌辅助化疗方案临床研究

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摘要 胃癌是我国最常见的消化道恶性肿瘤之一,5年生存率低于20%[1]。胃癌的治疗手段中,除手术外,其他治疗方法一概被称作辅助治疗。胃癌辅助化疗的经验来源于晚期胃癌的化疗[2]。术后辅助化疗的目的在于消灭亚临床转移灶或手术无法清除的残余癌,以达到根治肿瘤的效果。有大量研究结果显示,与单独手术相比,术后进行辅助化疗的3年生存率、无进展生存期和复发率均有改善趋势[3-4]。自从5-氟脲嘧啶出现后,新的化疗药物不断推出,化疗方案不断更新,学者们对各种单药、多药联合方案进行了大量的临床研究。虽然胃癌辅助化疗已有一定的历史,但对其效果一直存有争议。就现状而言,辅助化疗目前仅仅是对根治性手术的辅助治疗,实际效果亦未明确。
作者 张建 赵迎喜
出处 《医学信息(医学与计算机应用)》 2014年第14期617-617,共1页 Medical Information
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