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胱抑素C在乙肝后肝硬化患者肾功能损害早期诊断的应用价值 被引量:1

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摘要 目的:探讨血清Cys C检测对乙肝继发肝硬化患者肾功能早期损害的诊断价值。方法选择我院2012年4月~2013年4月收治的76例乙肝后肝硬化患者作为研究对象,根据Child-Pugh分级分为A级(21例)、B级(27例)、C级(28例),将同期在我院进行体检的38例健康患者对照,测定并比较四组患者血清内 SCr、BUN、Cys C及Ccr水平。结果肝功能C级组SCr、Cys C及Ccr水平显著高于健康组、肝功能B级组和C级组(P<0.05)。肝功能B级组Cys C及Ccr水平显著高于肝功能A级组和健康组患者水平(P<0.05)。SCr、Ccr水平与Cys C水平间均呈负相关关系,Cys C与Ccr间相关性更强。结论血清Cys C表达水平与乙肝后肝硬化严重程度密切相关,对于早期检测肾功能损害具有较好的敏感性和特异性。
作者 陈宏霞
出处 《医学信息(医学与计算机应用)》 2014年第2期152-153,共2页 Medical Information
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