摘要
目的:探讨宫颈阴道分泌物中胎盘α1微球蛋白(PAMG-1)联合HCG检测胎膜早破及预测早产的临床价值。方法对宫颈分泌物分别进行 PAMG-1联合HCG检测以及单纯PAMG-1、HCG检测,并对PAMG-1预测早产情况进行分析。结果 PAMG-1联合HCG检测同 PAMG-1比较,灵敏度、准确值和阴性预测值均具有统计学差异(P<0.05),但特异性、阳性预测值无统计学差异(P>0.05)。而同单独HCG检测比较,在所有方面都有统计学差异(P<0.05)。结论联合检测宫颈分泌物中 PAMG-1和HCG是诊断胎膜早破快速、准确的方法, PAMG-1对预测早产有积极的意义。
Objective:To investigate the placental alpha in cervicovaginal secretions 1 microglobulin(PAMG-1)combined with HCG detection of premature rupture of membranes and prediction of preterm labour.Methods:the cervical secretions were PAMG-1 combined with HCG detection and PAMG-1 alone,HCG detection,and the PAMG-1 prediction of preterm labor were analyzed.Results:PAMG-1 and HCG detection in comparison with PAMG-1,the sensitivity,accuracy and negative predictive values were statistical y dif erent(P<0.05),but the specificity,positive predictive value,no significant dif erence(P>0.05).With HCG detection alone,there are significant dif erences in al aspects(P<0.05).Conclusion:the combined detection of PAMG-1 and HCG in cervical secretion is the diagnosis of PROM,fast,accurate method,PAMG-1 has positive significance for the prediction of preterm delivery.
作者
薛芬
陶学强
XUE Fen;TAO Xue-qiang(Inner Mongolia Fourth Hospital of Baotou City,Obstetrics and Gynecology Department,Baotou Inner Mongolia 014030;Fourth Hospital of Baotou City Orthopedics V,Baotou Inner Mongolia,014030,China)
