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老年原发性高血压患者脂质代谢紊乱与血压变异性的相关性研究 被引量:1

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摘要 目的:探讨老年原发性高血压患者脂质代谢紊乱与血压变异性(BPV)情况及其二者的相关性。方法选取老年原发性高血压患者90例,检测其血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平,计算日间、夜间及24 h血压BPV。结果90例患者中,脂质代谢紊乱发生率为81.11%,其中高TC率为65.56%、高TG率为71.11%、高LDL-C率为58.89%、低HDL-C率为61.11%。 TC、TG、LDL-C异常组dSBP、nSBP、24h SBP的 BPV水平均高于正常组(t=3.19~4.07,P<0.05);HDL-C异常组dSBP、nSBP、24 h SBP的BPV水平均低于正常组(t=3.23~3.89,P<0.05)。 TC、TG、LDL-C与dSBP、nSBP、24 h SBP分别呈正相关(r=0.20~0.277,P<0.01);HDL-C与dSBP、nSBP、24 h SBP分别呈负相关(r=-019^-0.23,P<0.01)。结论老年原发性高血压患者具有较高的脂质代谢紊乱发生率,脂质代谢紊乱患者血压变异性水平较高,主要表现为收缩压波动较大,且与TC、TG、LDL-C呈正相关,与HDL-C呈负相关,其机制可能在于脂质代谢紊乱加剧了高血压患者的自主神经紊乱所致。
作者 董革 王芹
出处 《医学信息(医学与计算机应用)》 2014年第9期143-143,144,共2页 Medical Information
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