2012年天津市红桥区健康人群百日咳抗体水平调查

Investigation on Antibody Levels Against Pertussis,Among Healthy Population of Tianjin City in 2012

目的:调查评估天津市2012年健康人群中百日咳抗体水平。方法随机抽取健康人群血清199人份,分为10个年龄组,采用 ELISA法检测百日咳 IgG抗体。结果健康人群中,百日咳IgG抗体阳性率为8.54%,男性和女性没有差别,各个年龄组百日咳抗体阳性率差异有统计学意义(χ2=18.073,P=0.034<0.05)。其中,0~年龄组分别和4~、16~、21~年龄组百日咳抗体阳性率差异有统计学意义(χ2=5.517,P=0.044<0.05;χ2=6.545,P=0.031<0.05;χ2=5.775,P=0.04<0.05),2~年龄组分别和4~、16~、21~年龄组百日咳抗体阳性率差异有统计学意义(χ2=5.423,P=0.048<0.05;χ2=6.429,P=0.017<0.05;χ2=5.676,P=0.048<0.05)。结论抽取的天津市健康人群百日咳IgG抗体阳性率比较低.提示要扩大接种覆盖率。

Objective To survey and evaluate the antibodies levels against pertussis among healthy population of Tianjin City in 2012.Method ELISA was used to detect serum levels of IgG against pertussis in 199 healthy individuals who were divided into ten age groups.Results The antibody protection rates of pertussis was 8.54%.There was no statistical y significant dif erences between the two sexes and the dif erences were statistical y significant among the age groups(X2=18.073,P=0.034<0.05).There was statistical y significant between 0~and 4~,16~,21~group(X2=5.517,P=0.044<0.05;X2=6.545,P=0.031<0.05;X2=5.775,P=0.04<0.05)and there was statistical y significant between 2~and 4~,16~,21~group.(X2=5.423,P=0.048<0.05;X2=6.429,P=0.017<0.05;X2=5.676,P=0.048<0.05)Conclusions The antibody 1evel of pertussis in healthy population of Tianjin City is lower,which indicate that it is necessary to expand the vacination coverage rate.