摘要
过继免疫治疗是当前医学研究的重点内容,在细胞免疫中,A-NK细胞作为肿瘤过继免疫治疗(AIT)中的一种新型免疫效应细胞,具有短期内大量增殖,调节机体免疫能力,抗菌,抗病毒,抗衰老,抗肿瘤的特点受到普遍关注,临床应用也显示出广阔前景。本文追踪国际上研究进展就有关 A-NK细胞生物学特性,免疫调节及临床应用的研究现况及进展作以简要综述。
adoptive immunotherapy is the main content of the current medical research.In the cellular immunity,A-NK cells as the adoptive immunotherapy of tumor(AIT)is a new type of immune ef ector cells which have substantial proliferation in the short term,regulate the body's immunity,antibacterial,antiviral,anti-aging,anti-tumor features widely at ention.It also shows a broad clinical application prospect.This paper tracked the international research progress on A-NK cellbiological characteristics,immunity and clinical application research status.As wel the progress are reviewed.
作者
王志华
WANG Zhi-hua(Nanjing Qingan Hospital,Nanjing Jiangsu,210017,China;Harbin Medical University Cancer Institute,Harbin,Heilongjiang,150040,China)
基金
国家自然科学基金课题(39270765)
黑龙江省自然科学基金课题(201171).
