血清降钙素原、C反应蛋白、白细胞、与感染性疾病相关性的研究

Serum Procalcitonin, C-reactive Protein, White Blood Cells, and the Correlation of Infectious Diseases

目的:探讨血清降钙素原(procalcitonin,PCT)、C反应蛋白(C-reactive protein,CRP)、白细胞(white blood cel ,WBC)不同的测试水平在感染性疾病的相关性研究。方法用免疫色谱法、免疫浊度法对2680例受检者进行PCT、CRP定量检测,采用全自动血液分析仪检测受检者的外周血 WBC数。同时将3500例健康体检者的PCT、CRP,WBC作为对照组,并将它们的检测结果与临床诊断的相关性进行统计学分析。结果2680例感染性疾病患者血清 PCT、CRP、WBC在细菌感染组和非细菌感染组的阳性率分别为90.8%、56.9%、26.5%和9.7%、15.2%、11.1%,二者差异有统计学意义(P<0.01)。结论血清 PCT、CRP和 WBC测定可作为感染性疾病患者细菌感染性辅助鉴别指标,对指导抗生素的使用及病情评估,疗效判断有重要意义。

Objective Discusses the serum calcitonin(procalcitonin,PCT),c-reactive protein(C-reactive protein,CRP),white blood cells(white blood cell,WBC).Dif erent test level in the correlation of infectious diseases.Methods With immune chromatography,immune turbidity method 2680 cases of client holds the PCT,CRP on quantitative detection,The automatic detection of the client's blood analyzer peripheral blood WBC count.And at the same time,to 3500 cases of healthy check-up of the PCT,CRP,WBC as control group,and their testing results and the clinical diagnosis of the statistical correlation analysis.Results 2680 cases of infectious disease patients serum PCT,CRP,the WBC in bacterial infections group and the bacterial infection of positive group were 90.8%,56.9%,26.5%and 9.7%,15.2%,11.1%,both statistical y significant dif erence(P<0.01).Conclusion Serum PCT,CRP and WBC testing as a infectious disease patients identify bacteria infectious auxiliary indexes,the guidance antibiotic use and disease assessment,ef icacy judgment to have the important meaning.