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华法林对中老年非瓣膜病房颤患者抗凝作用的对比观察 被引量:1

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摘要 目的:观察华法林对于中、老年心房颤动患者抗凝治疗的有效性和安全性。方法选择2011年1月~2012年12月住院和门诊符合条件的90例心房颤动患者随机分为两组,华法林治疗组(治疗组)44例和对照组46例,治疗组给予口服华法林3mg/d,监测凝血酶原时间(PT)及国际标准化比值(INR)观察7~15d使 INR达到2.0~3.0范围内,以后查1次/月INR。对照组给予口服阿司匹林300mg/d,分2次进食时服用。结果治疗组有效42例,无效2例,有效率95.4%;对照组有效40例,无效6例,有效率86.9%。两组比较差异具有显著性(χ2=8,P<0.05)。结论中、老年非瓣膜病心房颤动患者选择华法令口服治疗,同时加强服药后监测,在临床上是安全、有效的。
作者 陈佳刚
出处 《医学信息(医学与计算机应用)》 2014年第6期74-74,共1页 Medical Information
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  • 1Ezekowize MD, Levine JA. Prevention stoke in patient with atrial fibrillation[J]. JAMA, 1999, 281:1830-1835.
  • 2Furberg CD. Prevalance of artrial fibrillatoon in elderly subjects[J]. Am J Cardiol, 1994, 74:236-241.
  • 3Afrial fibrillation investigators. Risk factios for stroke and efficacy of antithrombotic therapy in atrial fibrillation :analysis of pooled data from five randomized controlled trials[J]. Arch Intern Med, 1994, 154:1449-1457.
  • 4Mugge A. Anticoagulation in patient with AF[J].Herz, 1996,21 : 28-36.
  • 5Morley J,marineluk R, Rials ST, et al. Af,anticongulation and stroke[J], Am J Cardiol, 1996, 77:38-44.
  • 6Hylck EM,Skates SJ, Sheeham MA, et al. An analysis of the lowest effective intensify of prophy lactic anticongulation for patients with non-rheumatic atrial fibrillation[J]. N Eng J Med, 1996,335:540-546.
  • 7EAFT Study Group. European atrial fibrillation trial:secondary prevention of vascular events in patients with nonrheumatic atrial fibrillation and a recent transient ischemic attack or minor ischemic stroke.Lacent ,1993,342:1255~1262
  • 8The SPAF Ⅲ Writing Committee for the Stroke Prevention in Atrial Fibrillation Investigators. Patients with nonvalvular at long risk of strike during treatment with aspiring: strike prevention in atrial fibrillation Ⅲ study . JAMA, 1998,279:1273~1277
  • 9Ezekowitz MD ,Levine JA. Preventing stroke in patients with atrial fibrillation. JAMA,1999,281:1830-1835
  • 10Muramatsu H, Shimura T. Incidence of cerebral thromboembolic infarctiom associated with paroxysmal and persistent or permanent atrial fibrillation, JACC,2000,35(suppl A):103-104

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