摘要
Objective:To investigate the effects of laparoscopic hepatectomy and laparoscopic radiofrequency ablation on immune function, pain related indexes and liver function in patients with hepatocellular carcinoma.Methods: Ninety-six patients with hepatocellular carcinoma were randomly divided into two groups: control group and observation group. The patients in the control group were treated with laparoscopic hepatectomy, and the patients in the observation group were treated with laparoscopic radiofrequency ablation. The immune function, pain index and liver function were compared between the two groups.Results:There was no significant difference in the levels of CD3+, CD4+, CD8+, CD4+/CD8+, COR, NE, CRP, ALT and AST in two groups before treatment. After treatment, the levels of CD3+, CD4+and CD4+/CD8+ in the observation group were significantly higher than those in the control group. The levels of CD8+, COR, NE, CRP, ALT and AST in the observation group were significantly lower than those in the control group.Conclusion: Compared with laparoscopic hepatectomy, laparoscopic radiofrequency ablation for hepatocellular carcinoma can improve the immune function and liver function, reduce pain, and has certain clinical value.