摘要
Introduction Psoriasis is a chronic,immune-mediated inflammatory skin disease.The pathogenic characters of psoriasis are remarkable proliferation,unusual differentiation and immune activation of keratinocytes,accompanied with disorderly immune system[1].Psoriasis patients suffered from tremendous psychosocial burden,and remarkable reduction of physical activity and quality of life[2].
基金
CAMS Innovation Fund for Medical Sciences(No.CIFMS-2017-I2M-1-017)
the Natural Science Foundation of Jiangsu Province(No.BK20161123).