摘要
Objective To investigate the clinical characteristics and risk factors of infantile hemangioma in Xinjiang Uygur Autonomous Region,China.Methods A total of 941 infants with infantile hemangioma were identified as subjects and matched with 941 infants of the same age without infantile hemangioma.Trained investigators used a standardized questionnaire to collect data from both groups,including demographic,prenatal,and perinatal characteristics.Univariate and multiple logistic regression models were used to screen risk factors.Results This study revealed that female (P < 0.001,OR =3.08,95% CI =2.54-3.74),maternal tea drinking (P< 0.001,OR =1.86,95% CI=1.32-2.61),low birthweight (P< 0.001,OR =3.01,95% CI=2.10-4.30),preterm (P< 0.001,OR =4.07,95% CI=2.73-6.09),gestational diabetes (P < 0.001,OR =2.03,95% CI =1.41-2.94),maternal progesterone use (P <0.001,OR =2.44,95% CI =1.83-3.25) and a history of hemangiomas in first-degree relatives (P <0.001,OR =1.80,95% CI =1.33-2.43) influenced the occurrence of infantile hemangioma.Female (P < 0.001,OR =2.82,95% CI =2.30-3.45),maternal progesterone use (P < 0.001,OR =14.64,95%CI =3.52-60.88) and a history of hemangiomas in first-degree relatives (P< 0.001,OR =0.011,95%CI =0.002-0.065) were independent risk factors for infantile hemangioma.Conclusions Female,maternal tea drinking,low birthweight,preterm,gestational diabetes,maternal progesterone use,and a history of hemangiomas in first-degree relatives may interact with each other leading to the occurrence of infantile hemangioma.
