儿童期变应性疾病对注意缺陷多动障碍的影响

Atopic disease and attention deficit/hyperactivity disorder in children

近年来国内外多项研究均发现儿童多发的注意缺陷多动障碍(attention deficit/hyperactivity disorder,ADHD)与变应性疾病关系密切,两者常伴随发生,互为诱因,严重影响儿童的正常生长发育和身心健康.目前已有多篇关于ADHD与变应性疾病并发情况的综述及meta分析,从神经发育学和神经内分泌学及社会心理学等角度分析二者的关系.但是,两种疾病的相互作用尚未阐明,对于二者并发机制的探讨与研究结果尚无定论.该文通过对多篇中英文文献进行回顾性分析,对儿童期二者的并发情况进行简要介绍,并对关于儿童期变应性疾病对ADHD的影响这一问题的假设及实验结果进行综述,为今后对二者关系的研究提供帮助.

It is recently known that attention deficit/hyperactivity disorder(ADHD),which is often recognized in early-school children,may have a close relationship with atopic disease.Furthermore,there are numerous systemic reviews and meta-analysis focusing on the comorbidity of ADHD and atopic disease.However,the mechanism of the comorbidity has remained less well explored.This review aims to gain a better understanding of the relationship between ADHD and atopic disease in children,investigate the hypothesis and relevant studies results about the influences of atopic disease on ADHD,and help the correlative further research to some extent.