Anti-osteoporosis properties of phosphorylated collagen peptidemagnesium chelates in osteoblast MC3T3-E1 cells and ovariectomized mice

To the Editor:Postmenopausal osteoporosis is a typical bone metabolic disruption disease caused by estrogen deficiency,characterized by deteriorated bone structure,reduced bone mineral density(BMD),and thinned sclerotin,which has troubled millions of menopausal women worldwide.[1]Additionally,estrogen deficiency is accompanied by oxidative stress and inflammation,thus causing the occurrence and deterioration of osteoporosis.[2]Conventional treatment options have limited efficacy and cannot meet the requirements of long-term treatment.[3]Therefore,in order to alleviate the problem of osteoporosis in human health,innovative strategies should explore the possibilities and alternatives to current ones.In this study.