Efficacy and safety of bilastine vs.levocetirizine for the treatment of chronic idiopathic urticaria:A multicenter,double-blind,double-dummy,phase III,non-inferiority,randomized clinical trial

To the Editor:Chronic urticaria,prevalent globally and increasing in China,predominantly affects young and middle-aged women,impacting their quality of life(QoL).[1]Standard treatment involves second-generation H1 antihistamines,with bilastine showing promise due to its selective action and minimal side effects.However,direct comparative studies are scarce,particularly in the Chinese population.We aimed to evaluate the efcacy and safety of bilastine compared to levocetirizine in Chinese patients.