睡眠障碍与眼科疾病的关系研究进展

Research Progress of the Relationship between Sleep Disorders and Ophthalmic Diseases

随着经济的发展和生活方式的转变,睡眠障碍逐渐成为一种严重的公共卫生问题。近年来,越来越多的研究关注睡眠障碍与眼科疾病之间的关系,其原因可能与交感神经兴奋导致血管收缩,影响头面部的血管系统,缺氧诱导因子和炎症因子表达增加导致全身炎症和免疫失调及因夜间眼表暴露引起的机械损伤有关。现笔者对睡眠障碍与眼科疾病的关系研究进展进行综述,探讨睡眠障碍如何与眼科疾病相互影响,从而为临床医学提供更好的诊断和治疗方案。

With the development of the economy and changes in lifestyle,sleep disorders have gradually emerged as a significant public health issue.In recent years,there has been increasing researches focusing on the association between sleep disorders and ophthalmic diseases.The association may be attributed to sympathetic nervous system activation leading to vasoconstriction,increased expression of hypoxia-inducible factors and inflammatory factors resulting in systemic inflammation and immune dysregulation,as well as mechanical damage caused by overnight ocular surface exposure.In this paper,we reviewed the research progress on the relationship between sleep disorders and ophthalmic diseases,and explored how sleep disorders and ophthalmic diseases mutually influence each other,so as to provide better diagnosis and treatment for clinical medicine.