摘要
本文分析的临床资料来源于2016年1月至2022年12月湖南省人民医院肝胆外科,确诊为十二指肠乳头混合性神经内分泌-非神经内分泌肿瘤的7例患者。7例患者中,男5例,女2例,平均年龄59.3岁,其临床特点与壶腹部恶性肿瘤相似,较难鉴别,术前穿刺活检阳性率较低,术前诊断困难,预后较差,正电子发射计算机断层显像(PET/CT)对胃肠道神经内分泌肿瘤的辅助分级和预后评估有所帮助,包括手术、化疗和放疗在内的综合治疗或可作为本病首选的治疗方案。本组行腹腔镜下胰十二指肠切除术(LPD)者5例,行开腹胰十二指肠切除术(OPD)者2例,1例患者LPD术后因腹腔大出血死亡,其余患者术后均顺利出院。
The clinical data of 7 patients diagnosed with mixed neuroendocrine-nonneuroendocrine neoplasm were analyzed in the Department of Hepatobiliary Surgery of Hunan Provincial People′s Hospital from January 2016 to December 2022.Among the 7 patients,5 were male and 2 were female,with an average age of 59.3 years.Its clinical characteristics are similar to malignant ampulla tumors,and it is difficult to differentiate them.The preoperative puncture biopsy positivity rate is low,making it difficult to diagnose preoperatively,and the prognosis is worse.Comprehensive treatment including surgery,chemotherapy,and radiotherapy can be the preferred treatment option for this disease.
作者
姚清扬
钟震
李子涵
刘奔
毛先海
吕品
Yao Qingyang;Zhong Zhen;Li Zihan;Liu Ben;Mao Xianhai;Lyu Pin(Department of Hepatobiliary Surgery,the First Affiliated Hospital of Hunan Normal University,Hunan Provincial People′s Hospital,Changsha 410005,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2024年第16期1418-1421,共4页
National Medical Journal of China
基金
湖南省卫生健康委员会项目(D202304016577)
