体外二氧化碳清除在急性呼吸窘迫综合征救治中的应用价值

Clinical value of the implication of extracorporeal carbon dioxide removal in patients with acute respiratory distress syndrome

体外二氧化碳清除(ECCO_(2)R)是一种基于肺外气体交换的呼吸辅助体外生命支持技术,可以有效清除机体代谢生成的二氧化碳,以降低患者通气需求和呼吸机支持水平。随着体外生命支持相关技术的改进和临床经验的增多,研究提示ECCO_(2)R的临床应用具有潜在价值。本文阐述了ECCO_(2)R使用的原理、救治急性呼吸窘迫综合征(ARDS)的相关适应证、研究成果、存在的问题以及研究方向,以期为ARDS患者的救治提供更多参考。

Extracorporeal carbon dioxide removal(ECCO_(2)R)is a respiratory support technique based on extra-pulmonary gas exchange,which can effectively remove carbon dioxide generated in-vivo,reducing the requirements of respiratory support from mechanical ventilation.With improvements in extracorporeal life support technologies and increasing clinical experience,ECCO_(2)R has potential value in clinical application with acute respiratory distress syndrome(ARDS).This review article discusses the principles of ECCO_(2)R,its relevant indications for ARDS,clinical evidence,existing issues,and future directions,aiming to provide more references for the application in ARDS.