2017-2021年吉林省克山病年报数据分析

Analysis of annual report data of Keshan disease in Jilin Province from 2017 to 2021

目的掌握吉林省克山病病区范围及病情转归变化,为调整克山病防治工作重点提供科学依据。方法回顾性分析2017-2021年吉林省38个克山病病区县(市、区)上报的克山病年报数据,对克山病病区范围、人口数、现症患者一般情况及转归等进行描述性分析。结果截至2021年底,吉林省克山病病区范围总体无变化,病区县、乡、村常住人口数较2017年分别减少了11.77%、26.77%、35.55%;克山病现症患者共1092例,其中潜在型克山病926例、慢型克山病166例,男女性别比为0.38∶1.00(303∶789),≥60岁者占79.76%(871/1092),且有部分患者合并其他慢性病。2021年克山病患者较2017年减少1020例,死亡、迁出(入)、失访、重新诊断分别占转归总数的34.29%(500/1458)、27.85%(406/1458)、25.51%(372/1458)、12.35%(180/1458);60岁以下中青年死亡患者共57例;5年间新发现克山病患者24例,包括潜在型克山病4例、慢型克山病20例,且有6例慢型克山病患者在确诊2年内死亡。结论吉林省克山病病区范围总体无变化,常住人口数明显减少,现症患者老龄化,部分患者存在慢性病共病,死亡、迁出(入)、失访是现症患者转归的主要原因。

Objective To investigate the scope and changes in the outcome of Keshan disease in Jilin Province,and provide scientific basis for adjusting the focus of Keshan disease prevention and control.Methods A retrospective analysis was conducted on the annual report data of Keshan disease reported by 38 Keshan disease endemic counties(cities,districts)in Jilin Province from 2017 to 2021.Descriptive analysis was conducted on the scope of Keshan disease endemic areas,population,general situation and outcomes of current patients.Results As of the end of 2021,there was no overall change in the scope of Keshan disease endemic areas in Jilin Province.The number of permanent residents in counties,townships,and villages in the endemic areas had decreased by 11.77%,26.77%,and 35.55%,respectively,compared to 2017.There were a total of 1092 current patients with Keshan disease,including 926 cases of latent Keshan disease and 166 cases of chronic Keshan disease.The male to female ratio was 0.38∶1.00(303∶789),and 79.76%(871/1092)of the patients were over 60 years old.Some patients also had other chronic diseases such as hypertension and coronary heart disease.In 2021,the number of patients with Keshan disease decreased by 1020 compared to 2017.Death,migration(in),loss of follow-up,and re-diagnosis accounted for 34.29%(500/1458),27.85%(406/1458),25.51%(372/1458),and 12.35%(180/1458)of the total number of outcomes,respectively;57 middle-aged and young patients under 60 years old accounted for 11.40%(57/500)of the total deaths.Over the past 5 years,24 new patients were discovered,including 4 cases of latent Keshan disease and 20 cases of chronic Keshan disease.Additionally,6 patients with chronic Keshan disease died within 2 years of diagnosis.Conclusions The overall scope of Keshan disease endemic areas in Jilin Province has not changed,with a significant decrease in the number of permanent residents,an aging population of current patients,and some patients coexisting with chronic diseases.Death,migration(in),and loss of follow-up are the main outcomes of current patients.