肝脏单中心型Castleman病的诊断与治疗

Diagnosis and treatment of unicentric hepatic Castleman disease

单中心型Castleman病是一种罕见的异常淋巴组织增生性疾病,病因不明,其最常见组织病理学类型为透明血管型,临床表现为生长缓慢的孤立性肿块,主要发生于纵隔、腹腔、后腹膜、骨盆和颈部。采用多学科协作方式,对单中心型Castleman病进行诊断与治疗,以获得良好的治疗效果。单中心型Castleman病最佳治疗方法是手术切除,随着经验积累和技术进步,除开腹手术切除还有更精准微创的腹腔镜或机器人手术系统。笔者报道1例肝脏单中心型Castleman病诊断与治疗的临床经验,旨在为相关治疗提供参考。

Unicentric Castleman disease(CD)is a rarely abnormal lymphoproliferative disease with unknown etiology and hyaline vascular variant is the most common histopathological type.The clinical manifestations of unicentric CD are solitary masses with slow growth,mainly occurring in the mediastinum,abdominal cavity,retroperitoneum,pelvis,and neck.Application of multidisciplinary cooperation between surgical,radiologic,pathological and oncological experts is necessary for the diagnosis and treatment of unicentric CD,in order to achieve good treatment results.The best treatment method for unicentric CD is surgical resection.With the accumulation of experience and technological progress,there may be more precise and minimally invasive surgical methods such as laparoscopic or robotic techniques besides open surgery.The authors report the diagnosis and treatment of unicentric hepatic CD,aiming to provide reference for related treatments.