基于Web of Science的免疫疗法治疗变应性鼻炎文献计量学分析

Global research of immunotherapy on allergic rhinitis:a bibliometric analysis

目的利用VOSviewer及CiteSpace等软件探索免疫疗法治疗变应性鼻炎的研究热点以及发展趋势。方法使用Web of Science(WOS)核心数据库,检索免疫疗法治疗变应性鼻炎的相关文献并下载,运用VOSviewer和CiteSpace对文献的国家、机构、作者、关键词、引用情况进行可视化分析,运用WPS对相关数据进行统计分析。检索起止日期为1994年1月1日至2023年8月27日。结果本研究共纳入文献2846篇,其中发文量最多的是美国(567篇),发文量最多的机构是热那亚大学(102篇),且热那亚大学中心性达0.12,具有中介中心性;发文量排名前三的作者分别是Stephen R Durham(63篇),Giovanni Passalacqua(46篇),Oliver Pfaar(44篇);发文量排名前三的期刊分别是Allergy(222篇)、Journal of Allergy and Clinical Immunology(189篇)、Clinical and Experimental Allergy(141篇);关键词共现分析中,出现频次排名前三的分别是变异性鼻炎(allergic rhinitis,770次)、哮喘(asthma,362次)、舌下免疫治疗(sublingual immunotherapy,359次),提示变应性鼻炎与哮喘之间存在重要关联;关键词年度分布可视化图显示,近年研究热点有淋巴管内免疫疗法(intralymphatic immunotherapy)、皮下免疫疗法(subcutaneous immunotherapy)和免疫疗法(immunotherapy),其中淋巴管内免疫疗法排名第一。结论免疫疗法治疗变应性鼻炎的研究热度持续,美国在该领域发表论文最多,居引领位置;在发文机构中,热那亚大学具有中介中心性,起枢纽作用,是潜在的合作对象。研究前沿为"淋巴管内免疫疗法",可重点关注,推动免疫疗法治疗变应性鼻炎的进一步进展,为变应性鼻炎的治疗提供新的有效方法。

Objective To employ OSviewer and CiteSpace to explore the development trends and research hotspots of allergic rhinitis(AR)in the field of immunotherapy.Methods Web of Science(WOS)core collection was searched and the literature related to immunotherapy and AR retrieved.VOSivewer and CiteSpace were utilized for visually analyzing the country,institution,author,keywords and citations of the literature.Results Among a total of 2846 articles,the largest number of publications was the United States(567),institution with the largest number of publications University of Genoa(102)and centrality of University of Genoa 0.12.It attained betweenness centrality;Top 3 authors by number of publications were Stephen R Durham(63 articles),Giovanni Passalacqua(46 articles)and Oliver Pfaar(44 articles);Top 3 journals by number of publications were Allergy(222 articles),Journal of Allergy and Clinical Immunology(189 articles)and Clinical and Experimental Allergy(141 articles);Top 3 keywords were AR(770 times),asthma(362 times)and sublingual immunotherapy(359 times).It hinted at an important association between AR and asthma.From the perspective of overlay visualization.The hotspots were intralymphatic immunotherapy,subcutaneous immunotherapy and immunotherapy.The research frontier was intralymphatic immunotherapy.Conclusions Research popularity of immunotherapy for AR shall continue.The United States has published the most papers in this field and occupies a leading position.As for institutions,University of Genoa has betweenness centrality to play such a pivotal role that it is a potential institution to cooperate with.Research frontier of"intra-lymphatic immunotherapy"should be further explore for promoting the research advances of immunotherapy for AR.It can also provide solid theoretical rationales for offering a new and effective treatment of AR.