In vivo noninvasive study of diabetic peripheral neuropathy plantar morphology and mechanical properties based on ultrasound

To the Editor:The incidence of diabetes complications increases with the increase in diabetes incidence.Diabetic peripheral neuropathy(DPN)is one of the most common complications in diabetes patients.DPN is very harmful and is an important cause of diabetic foot and amputation.The amputation rate of DPN patients is 10-20 times higher than that of nondiabetic patients.Every 30 s,somewhere in the world,a patient’s lower limb or part of a lower limb will be surgically amputated due to DPN.[1]DPN seriously interferes with the physical and mental health of patients.At the same time,the high cost of treatment and rehabilitation care also causes huge economic pressure on patients.Therefore,it is particularly important to identify,diagnose,and prevent DPN in the early or ultra-early stage.