摘要
To the Editor:Upfront autologous stem cell transplantation(ASCT)has been an integral part of the management of young and eligible older patients with newly diagnosed multiple myeloma(NDMM)for over three decades.Tandem stem cell transplantation was defined as two planned sequential ASCTs within 3 to 6 months.More than two decades after its introduction,trials exploring the utility of tandem transplants have yielded mixed results.The role of tandem ASCT in multiple myeloma(MM)remains unclear and controversial.In the EMN02/HOVON95 study.
基金
supported by grants from the Department of Science and Technology of the Fujian Province Project(Nos.2017I0004 and 2017Y9057)
the Fujian provincial health technology project(No.2021ZD01005)
the National Key Clinical Specialty Discipline Construction Program(No.2021-76)
the Fujian Provincial Clinical Research Center for Hematological Malignancies(No.2020Y2006)
the Fujian Provincial Key Clinical Specialty Discipline Construction Program.
