摘要
Hepatocellular carcinoma(HCC)is the most common type of primary hepatocellular carcinoma(PHC).Early diagnosis of HCC remains the key to improve the prognosis.In recent years,with the promotion of the concept of precision medicine and more in-depth analysis of the biological mechanism underlying HCC,new diagnostic methods,including emerging serum markers,liquid biopsies,molecular diagnosis,and advances in imaging(novel contrast agents and radiomics),have emerged one after another.Herein,we reviewed and analyzed scientific advances in the early diagnosis of HCC and discussed their application and shortcomings.This review aimed to provide a reference for scientific research and clinical practice of HCC.
基金
Natural Science Foundation of China(No.81902484)
China Postdoctoral Science Foundation(No.2020M670864)
Medical and Health Talents Project of Jilin Province(Nos.2019SCZT003,2020SCZT096)
Youth Support Project of Jilin Association for Science and Technology(No.202028)
Project of Hepatobiliary and Pancreatic Disease Translational Medicine Platform Construction(No.2017F009)