摘要
To the Editor:Non-alcoholic fatty liver disease(NAFLD)becomes a worldwide epidemic with a currently estimated prevalence of 24%.The spectrum of NAFLD includes simple steatosis and non-alcoholic steatohepatitis.Folate,also called vitamin B9,is the generic term given to a family of compounds,including unsubstituted tetrahydrofolate(THF),5-methyltetrahydrofolate(5-MTHF),5-formyltetrahydrofolate(5-FTHF),5,10-methylene-THF(5,10-CH_(2)-THF),and unmetabolized folic acid(UMFA).Folic acid is usually added to products as a dietary supplement.
基金
supported by the National Natural Science Foundation of China(No.82070585)
the Natural Science Foundation of Zhejiang Province(No.LY21H030001)
and the Health Science and Technology Plan Project of Zhejiang Province(Nos.2021KY1129 and 2022KY1274).
