Timing,approach,and treatment strategies for infected pancreatic necrosis:a narrative review

Pancreatic necrosis occurs in approximately 15%to 20%of patients with acute pancreatitis(AP);1/3 of patients are diagnosed with infected pancreatic necrosis(IPN),which has a mortality rate of 30%.It is the chief reason for the second“death peak”of AP patients in the later stage of the disease.[1]As one of the most vital treatment methods for IPN,pancreatic necrosectomy has developed rapidly in the past 30 years,including improvements and breakthroughs in surgical timing,approach,and strategies,and a significant reduction in postoperative mortality from the initial 30%to 40%.