影像学引导下不可逆电穿孔消融治疗肾癌专家建议(2023版)

Expert recommendation on image-guided irreversible electroporation ablation treatment for renal carcinoma(2023 edition)

不可逆电穿孔消融治疗能够在损毁肿瘤细胞的同时保留周围重要生理结构的完整,适用于肾细胞癌不可外科切除或不愿外科切除的患者,能够最大程度保证术后肾功能的良好,具有其他温度消融治疗所不具备的优势。但由于不可逆电穿孔治疗对电极针布针和参数设定要求较高,不当操作将直接影响患者的预后。为提高肾癌综合治疗水平,规范不可逆电穿孔治疗肾细胞癌的操作技术,由中国医药教育协会介入微创治疗专业委员会牵头制定了“影像学引导下不可逆电穿孔消融治疗肾癌专家建议(2022版)”。本文详细介绍了不可逆电穿孔治疗肾癌的适应证、禁忌证、围手术期准备、操作基本原则、并发症及其相关处理和随访等内容,以便为临床实践提供参考。

Irreversible electroporation ablation therapy can destroy tumor cells while retaining the integrity of the important surrounding physiological structures.It is suitable for patients with renal cell carcinoma who cannot be surgically resected or who do not want surgical resection,and can ensure the best postoperative renal function to the greatest extent,and has advantages that other thermal ablation treatments do not have.However,since irreversible electroporation therapy has high requirements for electrode needles and parameter settings,improper operation will directly affect the prognosis of patients.In order to improve the level of comprehensive treatment of renal cell cancer and standardize the operation technique of irreversible electroporation for renal cell carcinoma,the Committee of interventional minimally invasive therapy of the Chinese Medical Education Association took the lead in formulating the Expert Recommendation on image-guided irreversible electroporation ablation for Renal Cancer(2022 edition).The article introduces in detail the indications,contraindications,perioperative preparation,basic principles of operation,complications and related management and follow-up of irreversible electroporation for renal cell carcinoma,in order to provide reference for clinical practice.