摘要
子宫内膜异位症是临床常见妇科疾病之一,由于其临床症状出现较晚且缺乏特异性及敏感性,严重影响内异症的诊断及早期干预。近几年,代谢组学技术广泛用于内异症的研究,本文旨在总结近些年代谢组学技术在内异症中的研究进展,并归纳内异症患者的卵泡液、血清、尿液及内膜组织等方面的相关生物标志物,并对其代谢组学特征进行阐述。
Endometriosis is one of the most common gynecological diseases in clinical practice.Due to its late onset of clinical symptoms and lack of specificity and sensitivity,the diagnosis and early intervention of endometriosis are seriously affected.In recent years,metabonomics technology has been widely used in the study of endometriosis.This paper aims to summarize the research progress of metabonomics technology in endometriosis in recent years,and summarize the biomarkers related to follicular fluid,serum,urine and intimal tissue of endometriosis patients,and elaborate their metabonomics characteristics.
作者
王宁
吴慢莉
杨东霞
Wang Ning;Wu Manli;Yang Dongxia(Department of Integrated Chinese and Western Medicine,Handan First Hospital,Handan City,Hebei Province,Handan 156001,China;Department of Gynecology,Heze Hospital of Traditional Chinese Medicine,Heze 274002,China;Second Department of Gynecology,the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150000,China)
出处
《中华临床医师杂志（电子版）》
CAS
北大核心
2022年第12期1280-1283,共4页
Chinese Journal of Clinicians(Electronic Edition)
基金
国家自然科学基金项目(81574015)
黑龙江省自然科学基金项目(LH2020H087)
国医大师孙申田教授“经颅重复针刺法”调控p38-MAPK通路抑制EMs疼痛中枢敏化机制研究(GY2022-25)
黑龙江中医药大学研究生创新科研项目(2020yjscx047)
黑龙江省中医药管理局国医大师学术思想传承科研课题(GY2022-25)
