《中国妊娠期与哺乳期乳腺癌临床实践指南(2022版)》基本问题解读

Interpretation of basic contents of Clinical Practice China Guidelines for Breast Cancer during Pregnancy and Lactation (2022 edition)

妊娠期与哺乳期乳腺癌由于生理上的改变以及诊疗措施可能对子代产生影响,其临床诊治具有独特性与复杂性。然而,国内相关研究较少且缺乏规范的临床诊治流程。中华医学会外科学分会乳腺外科学组组织编写的《中国妊娠期与哺乳期乳腺癌临床实践指南(2022版)》参考GRADE系统标准将临床研究证据分类,优先选择Ⅰ类和Ⅱ类证据纳入评价体系,并结合中国临床研究特点和临床实践的可及性作出不同强度的推荐意见。本文对该指南中的基本问题进行解读,以期为国内乳腺外科医师临床工作提供参考。

Because of the physiological changes and the possible affection of diagnostic and treatment measures,the clinical management of breast cancer during pregnancy and lactation is unique and complex.However,there is only little related research and no standardized clinical diagnosis and treatment procedures exist in China.Therefore,the Chinese Society of Breast Surgery evaluated the level of evidence in clinical research of breast cancer during pregnancy and lactation by referring to the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system.Based on the currently available high-quality levelⅠorⅡevidence,the clinical characteristics of patients,and the accessibility of the clinical practice of breast surgery,the Clinical Practice Guideline for Breast Cancer during Pregnancy and Lactation 2022 was formulated.This article interprets the basic contents of the guidelines to provide reference for the clinical work of breast surgeons in China.