宫腔镜电切术联合生化汤加减治疗子宫内膜息肉的疗效及对短期复发的影响

Efficacy of hysteroscopic electroresection combined with modified Shenghua decoction for treatment of endometrial polyps and its impact on short-term recurrence

目的分析宫腔镜电切术联合生化汤加减对子宫内膜息肉的疗效及对短期复发的影响。方法将2020年1月至2021年3月江苏省连云港市中医院收治的132例子宫内膜息肉患者随机分为观察组和对照组,每组各66例。对照组采取宫腔镜电切术和术后规范口服妈富隆治疗,观察组在此基础上给予生化汤辩证加减治疗。比较2组患者治疗效果及术后≥6个月短期复发情况。结果观察组治疗总有效率为90.91%,明显高于对照组的62.12%(P<0.05)。术后3个月时2组患者子宫内膜厚度、月经量及经期均明显改善,较术前比较差异均有统计学意义(P<0.05);而且观察组患者子宫内膜厚度、月经量及经期改善情况明显优于对照组(P<0.05)。术后3个月时2组患者血清LH、E_(2)、FSH水平均较术前明显下降,差异均有统计学意义(P<0.05);观察组患者血清激素水平均明显低于对照组(P<0.05)。术后6-20个月观察组复发率为3.03%,对照组为12.12%(P<0.05)。结论生化汤加减辅以宫腔镜电切术可降低子宫内膜息肉患者术后短期复发风险。

Objective To observe the clinical efficacy of hysteroscopic electrocision combined with modified shenghua decoction in the treatment of endometrial polyps and explore its effect on short-term recurrence.Methods A total of 132 cases of endometrial polyps treated at Lianyungang Hospital of Traditional Chinese Medicine from January 2020 to March 2021 were selected as the research subjects,and they were randomly divided into an observation group and a control group using the random number table method,with 66 cases in each group.The therapeutic effects and short-term recurrence after≥6 months were compared between the two groups.Results The total effective rate in the observation group was 90.91%,which was significantly higher than that in the control group(62.12%;P<0.05).Three months after surgery,the endometrial thickness,menstrual flow,and menstrual period were significantly improved in both groups compared with those before surgery(P<0.05).The improvements of endometrial thickness,menstrual flow,and menstrual period in the observation group were significantly superior to those in the control group(P<0.05).In particular,serum LH,E_(2),and FSH levels of patients in the observation group were significantly lower than those in the control group(P<0.05).The recurrence rate was 3.03%in the observation group and 12.12%in the control group within 6~20 months after operation,and the difference was statistically significant between the two groups(P<0.05).Conclusion Short-term recurrence risk can be reduced after hysteroscopic resection of endometrial polyps supplemented with modified Shenghua decoction.