老年外科患者虚弱研究进展

Advances in research of frailty in elderly surgical patients

虚弱是指机体的储备功能和认知功能下降,导致对压力源的易感性增加。其表现包括减少的活动耐量、肌肉含量以及不良的营养状态,且往往与疾病症状加重和术后不良结局有关。目前,临床上尚无评估虚弱状态的金标准。本文主要针对国内外常用的虚弱评估方法、临床应用、预防策略以及相关机制进行系统的综述。

Frailty refers to a decrease in the body's reserve and cognitive functions,leading to an increased susceptibility to stressors.The manifestations of frailty include reduced activity tolerance and muscle content and poor nutritional status,and it is often associated with worsening disease symptoms and adverse postoperative outcomes.There is currently no gold standard for evaluating frailty in clinical practice.This article mainly provides a systematic review of commonly used frailty assessment methods,their clinical applications,and the prevention strategies for and related mechanisms of frailty.