射频消融用于关节软骨损伤的治疗研究进展

Research progress of radiofrequency ablation in treatment of articular cartilage injury

软骨损伤普遍出现在正常人群中,严重影响了人们的日常生活与工作,然而软骨损伤仍是临床治疗的一个巨大挑战。机械清理、激光等传统软骨成形术由于其缺陷,无法满足临床应用的需求。射频软骨成形术作为一种更加安全、有效的技术,逐渐成为研究的热点。虽然基础研究表明射频产生的局部高温可能造成软骨细胞的死亡,但在长期的临床随访研究中,大量证据表明,相比机械清理软骨成形术,射频软骨成形术取得了更好的结果,并在一定程度上延缓了骨关节炎的进展。在使用的过程中,需要通过对射频使用时间、探头距离、灌洗液的流量和温度等方面的控制,来保证其安全性。本文通过简要介绍射频的历史、机制,综述了射频的临床应用结果,讨论如何更安全、有效地使用射频处理软骨损伤。

Cartilage injury is common in normal population,which seriously affects people′s daily life and work.However,cartilage injury is still a great challenge in clinical treatment.The traditional chondroplasty,such as mechanical debridement and laser,cannot meet the needs of clinical demands due to their defects.Radiofrequency chondroplasty,as a safer and more effective technique,has gradually become a research hotspot.Although basic studies have shown that local heat generated by radiofrequency may contribute to chondrocyte death.In long-term clinical follow-up studies,there is substantial evidence that radiofrequency chondroplasty obtains better outcome and somewhat delays the progression of osteoarthritis compared to mechanical debridement.When using radiofrequency,clinicians need to control the use time,distance of the radiofrequency probe,flow and temperature of the lavage fluid to ensure its safety.This article briefly introduced the history and mechanism of radiofrequency,summarized the clinical application results of radiofrequency,and discussed how to use radiofrequency more safely and effectively.