炎症标志物与老年衰弱综合征

Inflammatory markers and frailty in the elderly

老年衰弱综合征是老年人群常见的致残性因素,机体的炎症过程与老年衰弱之间存在密切联系。近年来,研究人员对炎症标志物在老年衰弱综合征中的作用进行了广泛的研究,这些标志物包括细胞因子、白细胞、氧化应激指标、C反应蛋白、肿瘤坏死因子等。本文回顾目前关于炎症标志物与老年衰弱综合征的研究成果,分析它们在诊断、预测和干预老年衰弱综合征方面的潜在应用价值,以便于临床筛选老年衰弱综合征的干预靶点,促进更有效的预防和管理策略,从而提升老年人群的健康和生活质量。

Geriatric frailty syndrome is a common debilitating condition among the elderly population,which is closely associated with systemic inflammation processes.In recent years,researchers have extensively studied the role of inflammatory biomarkers in geriatric frailty,including cytokines,white blood cells,oxidative stress indicators,C-reactive protein,tumor necrosis factor,etc.This paper aims to review the current research findings on the relationship between inflammatory biomarkers and geriatric frailty syndrome,analyzing their potential value in diagnosis,prediction,and intervention of frailty in the elderly,facilitating the development of more effective strategies for prevention and management,ultimately improving the health and quality of life of the elderly.