梨状窝癌向甲状软骨、甲状腺侵犯的组织病理学研究

Histopathological study on the pyriform sinus carcinoma invading thyroid cartilage and thyroid gland

目的 :了解梨状窝癌 (pyriformsinuscarcinoma ,PSC)较恶劣的生物学行为 ,掌握其易向邻近组织、器官侵犯的特性 ,手术治疗是头颈外科领域的一个难题。研究PSC向邻近组织的侵犯规律。方法 :采用连续切片的方法对梨状窝癌术后离体标本进行组织病理学研究。结果 :喉软骨中甲状软骨最易受侵犯 ,其内壁受侵的频度最高 ;PSC对喉软骨的挤压推进式侵犯明显多于浸润破坏式。结论 :喉软骨和软骨膜是抵抗肿瘤侵犯的解剖屏障 ;甲状软骨的下缘。

The surgical specimen from total laryngectomy and partial hypopharyngectomy in 43 cases of pyriform sinus carcinoma were histopathological studied by whole tissue serial sectioning .The results are as follows:In laryngeal ones the thyroid cartilages were invaded more frequently than the othesrs,and particularly the interior wall of which was invaded in the highest frequency.Invasion of laryngeal cartilage in pushing and pressing pattern was obviously more common than those in infiltrating and destroying on...