新生儿窒息与高血糖相关性探讨

Studies the relation between asphyxia neonaturum and hyperglycemia

目的 探讨新生儿窒息和高血糖的相关性。方法 动态监测窒息新生儿血糖及其4种调节激素;皮质醇(CT)、胰岛素(INS)、胰高血糖素(GC)和生长激素(GH)。结果 轻度窒息组出现高血糖21例(17.9％),重度窒息组高血糖19例(38％);轻度窒息4种激素与对照组比较无显著性差异,多元线性回归分析表明血糖与INS呈负相关(r=0.8429),与其它3种激素无相关;重度窒息组4种激素明显升高,多元线性回归分析表明重度窒息组6～12小时血糖与CT和GC水平呈显著性正相关(r分别=0.88和0.69,P<0.01),与INS和GH无相关(r分别=0.17、0.14,P>0.01)。结论 应急状态是窒息新生儿血糖升高的主要原因,新生儿窒息时的血糖明显升高可能是病情严重的信号,可作为病情严重程度及预后的判断指标之一,具有一定的价值。

objective To study the relation between asphyxia neonaturum and hyperglycemia. Methods the blood sugar and four major hormonal control factors of glucose production were contiuously measured during the first 3 days of life in 157 asphyxiated term newborns: cortisol (CT). glucagons (GC), growth hormone (GH) and insulin (INS). Results there were 21 (17. 9%) hyperglycenia in the group of the gentle asphyxia (group I), and 19 (38%) hyperglycenia in the group of the heavy asphyxia (group II), While INS ...