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纤溶酶原激活物抑制剂-1基因多态性与冠心病的关系

Relationship between the gene polymorphism of plasminogen activator inhibitor-1 and coronary heart disease
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作者 袁向阳
出处 《华北煤炭医学院学报》 2007年第2期172-174,共3页 Journal of North China Coal Medical College
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参考文献22

  • 1[1]Henry M,Tregouet DA,Alessi MC,et al.Metabolic deteminants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations:a family study with part of the Stanislas Cohort[J].Arterioscler Thromb Vasc Biol,1998,18 184
  • 2[2]Dawson S,Hamsten A,Wiman B,et al.Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity[J].Arterioscler Thromb.1991,11:183
  • 3[3]Zalewski A,Shi Y,Nardone D,et al.Evidence for reduced fibrinolytic activity in unstable angina at rest:clinical biochemical and angiographic correlates[J].Circulation,1991,83:1685
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  • 5[5]Kimura H,Gejyo F,Suzuki Y,et al.Polymorphisms of angiotensin coverting enzyme and plasminogen activator inhibitor-1 gene in diabetes and macroangiopathy[J].Kidney Int,1998,54:1659
  • 6[6]Mansfield MW,Stickland MH,Grant PJ.Environmental and genetic factors in relation to elevated circulating levels of plasminogen activator inhibitor-1 in Caucasian patients with non-insulin-dependent diabetes mellitus[J].Thromb Haemost,1995.74:842
  • 7[7]McCormack LJ,Nagi DK,Stickland MH,et al.Promoter(4G/5G)plasmi-nogen activator inhibitor-1 genotype in Pima Indians:relationship to plasminogen activator inhibitor-1 levels and feature of the insulin resistance syndrome[J].Diabetologia,1996,39:1512
  • 8[8]Kain K,Young J,Bamford J,et al.Determinants of plasminogen activator inhibitor-1 in South Asians with ischaemic stroke[J].Cerebro-vasc Dis,2002,2:77
  • 9[9]Rizzo MR,Ragno E,Barbieri M,et al.Elevated plasma activator inhibitor-1 is not related to insulin resistance and to gene polymorphism in healthy centenarians[J].Atherosclerosis,2002,160:385
  • 10[10]Hoffstedt J,Andersson IL,Persson L,et al.The common-675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is strongly associated with obesity[J].Diabetologia,2002,45:584

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