气血理论在慢性肝病肝纤维化治疗中的指导作用

Guiding Role of Qi-blood Theory in Treatment of Liver Fibrosis Due to Chronic Liver Diseases

肝纤维化是慢性肝病的共同病理特征,属于中医"癥积"、"胁痛"等范畴。其病机与中医肝脏及气血功能失调有密切关系。在慢性肝病肝纤维化的早期阶段,多以气滞血瘀为主,或兼血热;病程日久,正气渐虚,则以气(血)虚血瘀为主要表现。目前临床治疗肝纤维化的有效方药多包含有"益气"、"理气"、"化瘀"与"养(阴)血"等作用。因此临床治疗慢性肝病肝纤维化宜重视调理气血,包括理气、益气、活血与养血,尤其是益气活血。

Hepatic fibrosis is the common pathological feature of chronic liver diseases, which belongs to 'mass in the abdomen', 'hypochondriac pain' in TCM. The pathogenesis of liver fibrosis is connected with dysfunction of qi and blood. In the early stage of hepatic fibrosis, the basic pathological factor is qi stagnancy and blood stasis combinde with or without heat in blood; while in the advanced stage, it is qi deficiency and blood stasis. The effective prescriptions in treating hepatic fibrosis are usually composed of herbs with the functions of tonifying qi, regulating qi, activating blood to resolve stagnation and nourishing blood or yin. The main principle for treating hepatic fibrosis due to chronic liver diseases is regulating qi and blood or, including regulating qi, tonifying qi, activating blood to resolve stagnation and nourishing blood or yin, especially tonifying qi and activating blood to resolve stagnation.