肺癌骨转移核素骨显像的临床分析

Radionuclide bone imaging in diagnosis of bone metastasis in lung cancer

目的:分析肺癌骨转移特点,评估单光子发射计算机断层显像术(SPECT)放射性核素骨显像诊断肺癌骨转移的价值。方法:收集肺癌骨转移SPECT核素骨显像113例,对骨转移部位、数量与病理类型进行回顾性分析。结果:113例肺癌骨转移患者中,多发骨转移71例,占骨转移者62.8%。各病理类型中,其中以腺癌多发骨转移最为常见达72.5%。骨转移病灶分布以脊柱最多(38.6%),其次为肋骨、骨盆、四肢骨、颅骨、肩胛骨和锁骨。结论:肺癌骨转移以多发性病灶较为常见,骨转移部位以脊椎骨、肋骨多发,腺癌最易发生骨转移。肺癌患者应常规进行骨扫描,这对疾病的分期、治疗方案的选择、预后的评价均有重要的意义。

Objective:To explore the characteristics of bone metastasis and to investigate the diagnostic value of radionuclide bone imaging in patients with lung cancer.Methods:Bone metastatic sites,quantity and different pathological types were analyzed retrospectively in 113 cases of skeletal metastases patients with lung cancer in past three years.Results:Among the 113 patients,62.8% patients were multiple bone metastasis.Most metastatic sites were in spine,and others were in rib,pelvis,and skull.Conclusions:Multiple bone metastasis is one of the characters of lung cancer.The thorax and thoracic spine is the most frequent metastatic sites.Bone metastasis of squamous carcinoma was more easily than other types of lung cancer.Radionuclide bone scan is the most sensitive method for the diagnosis of osseous metastasis.All the patients with lung cancer should be performed radionuclide bone scan,which is significant for staging,selecting therapy methods and the evaluating prognosis of the disease.