期刊文献+

老年性黄斑变性的药物治疗研究新进展

Progressions in medication of age-related macular degeneration
下载PDF
导出
摘要 老年性黄斑变性是老年人的主要致盲眼病之一。近年来对老年性黄斑变性相关性脉络膜新生血管的药物治疗研究有了显著进展,在对抗血管内皮生长因子、人工合成的皮质激素、色素上皮源性因子、蛋白激酶C抑制剂、环氧化酶-2抑制剂、尿激酶纤溶酶原激活剂-受体系统抑制剂等药物的临床和实验研究取得了可喜的成果,尤其是抗血管内皮生长因子的各种药物的临床应用已显示明显疗效,为患者带来了复明的希望。
出处 《四川生理科学杂志》 2007年第3期131-134,共4页 Sichuan Journal of Physiological Sciences
  • 相关文献

参考文献21

  • 1[1]Heier JS.Review of Lucentis(ranibizumab,rhuFab V2) phase I/II trial results:6-month treatment of exudative AMD[J].Invest Ophthalmol Vis Sci.2004;45:ARVO E-Abstract 1109 and paper discussion.
  • 2[2]Eyetech Study Group.Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration:phase II study results[J].Ophthalmology.2003;110:979-986.
  • 3[3]The Eyetech Study Group.Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration[J].Retina.2002;22:143 -152.
  • 4[4]P van Wijngaarden.Inhibitors of ocular neovascularization:promises and potential problems[J].JAMA.2005;293:1509.
  • 5[5]Carrasquillo KG,Ricker JA,Rigas IK,et al.Controlled delivery of the anti-VEGF aptamer EYE001 with poly (lactic-co-glycolic) acid microspheres[J].Invest Ophthalmol Vis Sci.2003;44:290-299.
  • 6[6]Anecortave Acetate Study Group.Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration:twelve-month clinical outcomes[J].Ophthalmology.2003;110:2372-2383.
  • 7[7]Ciulla TA,Criswell MH,Danis RP,et al.Squalamine lactate reduces choridal neovascularization in a laser-injury model in the rat.Retina,2003;23:808-814.
  • 8[8]Higgins RD,Yan Y,Geng Y,et al.Reg ression of retinopathy by Squalamine in a mouse model[J].Pediatr Res.2004;56:144-149.
  • 9[9]Garcia CA,Quiroz-Mercado H,Uwaydat S,et al.A phase I/II trial of intravenous squalamine lactate for treatment of choroidal neovascularization in age-related macular degeneration (ARMD)[J].Invest Ophthalmol Vis Sci.2004;45:ARVO E-Abstract 2362.
  • 10[10]Mori K,Gehlbach P,Ando A,et al.Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor.Invest Ophthalmol Vis Sci.2002;43:2428-2434.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部