小儿moyamoya病颞浅动脉组织学和超微结构与免疫组化研究

A Histopathological ultrastructural and immunohistochemical study on superficial temporal arteries in children with moyamoya disease

报告了５例小儿ｍｏｙａｍｏｙａ病（ＭＤ）颞浅动脉（ＳＴＡ）的组织学和超微结构病理，它们的变化是中膜平滑肌细胞变性、破坏，内弹力板变薄、断裂和内膜平滑肌细胞增生。这些变化与成人ＭＤ脑动脉和ＳＴＡ的病变一致。小儿ＭＤ的ＳＴＡ中能看到大量较早期和较轻的病变，如中膜平滑肌细胞空泡变性、质膜破坏、或仅见于内弹力板两侧的肌细胞坏死；内弹力板破坏轻；内膜增生轻，没有管腔狭窄，与成人不同。本文对ＭＤ动脉病变的发展过程和病因问题提出了看法。

Histological and ultrastructural pathology in superficial temporal arteries(STA)of 5 children with moyamoya disease(MD)was reported.The main pathological changes were:degeneration and destruction of smooth muscle cells(SMCs) in media,thinning and fragmentation of elastica interna(EI),and proliferation of SMCs in intima. These changes were similar to those in cerebral arteries and STA of adult patients with MD.In children with MD,many earlier and milder pathological changes could be seen in STA, e, g.vacuola...