摘要
目的 评价控释药氯己定薄片 (chip)辅助牙周刮治 (scalingandrootplaning,SRP)治疗牙周炎的疗效和安全性。方法 6 5例成人牙周炎患者经全口SRP后 ,左右侧象限均至少有一个牙位探诊深度 (probingdepth ,PD)≥ 5mm且探诊出血 (bleedingonprobing ,BOP) ,选此种牙为受试牙 ,检查和记录其临床指标 ,并随机选择一侧的受试牙刮治后放药 ,另一侧受试牙刮治后不做处理 ,临床观察 6个月。结果 用药组在第 6个月时的PD减少 (1 32mm)以及附着增加 (0 91mm)均显著高于对照组(0 77mm ,0 40mm) ,差异有非常显著性 (P <0 0 0 1) ,第 6个月用药组的BOP阳性率 (79 4% )明显低于对照组 (92 4% ) (P <0 0 0 1) ;两组的牙面着色指数无统计学差别。 44 6 %的患者反映用药部位不适 ,主要为牙龈轻度胀痛。结论 SRP +氯己定薄片组在减少PD、增加牙周附着和减轻牙周组织炎症方面优于单纯SRP组 。
Objective To evaluate the clinical efficacy and safety of the adjunctive use of Chlorhexidine Chip (CHX; commercial name, Perio Chip) following scaling and root planing (SRP) in periodontitis. Methods One center, blinded, randomized, split mouth and active control study was designed. Sixty five adult periodontitis patients were enrolled into the baseline after SRP. Each subject had at least one tooth with pocket depth of 5 mm or more and bleeding on probing (BOP) in each side of the mouth. Then the to...
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2001年第6期46-48,共3页
Chinese Journal of Stomatology
关键词
牙周炎
药物治疗
氯己定
Periodontitis
Drug therapy
Chlorhexidine
